Generic Name: chromium picolinate (KROME ee um pi KOE li nate)
Brand Names: Cr-GTF, CRM
What is CRM (chromium picolinate)?
Chromium is a mineral found in certain foods. The body needs only trace amounts of chromium, and deficiency of this mineral in humans is rare.
Chromium picolinate works together with insulin produced by the pancreas to metabolize carbohydrates.
Chromium picolinate has been used in alternative medicine as an aid to lowering cholesterol or improving the body's use of glucose (sugar). It is also commonly touted as a weight-loss supplement that aids in reducing body fat and increasing lean muscle.
Not all uses for chromium picolinate have been approved by the FDA. Chromium picolinate should not be substituted for prescription medications.
Chromium picolinate is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Chromium picolinate may also be used for other purposes not listed in chromium picolinate guide.
What is the most important information I should know about CRM (chromium picolinate)?
Not all uses for chromium picolinate have been approved by the FDA. Chromium picolinate should not be substituted for prescription medications.
Chromium picolinate is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Use chromium picolinate as directed on the label, or as your doctor has prescribed. Do not use this product in larger amounts or for longer than recommended.
Your healthcare provider may occasionally change your dose to make sure you get the best results from chromium picolinate. The recommended dietary allowance of chromium increases with age. Follow your healthcare provider's instructions.
Your dose needs may change if you have an injury, illness, or infection, if you are pregnant, if you are under stress, or if you exercise more than usual.
Chromium picolinate is only part of a complete program of treatment that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Tell your healthcare provider about all other medications you use, especially insulin or diabetes medications you take by mouth, steroid medications, nicotinic acid, stomach acid reducers, asthma or blood pressure medications, aspirin, or an NSAID (non-steroidal anti-inflammatory drug).
What should I discuss with my health care provider before taking CRM (chromium picolinate)?
Before using chromium picolinate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use this product if you have:
liver disease;
diabetes;
cancer; or
a weak immune system.
Chromium picolinate may be harmful to an unborn baby. Do not use this product without talking to a healthcare provider if you are pregnant or plan to become pregnant during treatment. Chromium picolinate may pass into breast milk and may harm a nursing baby. Ask your healthcare provider before using this product if you are breast-feeding a baby. Do not give any herbal/health supplement to a child without the advice of a doctor.
How should I take CRM (chromium picolinate)?
When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.
If you choose to take chromium picolinate, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.
Your healthcare provider may occasionally change your dose to make sure you get the best results from chromium picolinate. The recommended dietary allowance of chromium increases with age. Follow your healthcare provider's instructions. You may also consult the National Academy of Sciences "Dietary Reference Intake" or the U.S. Department of Agriculture's "Dietary Reference Intake" (formerly "Recommended Daily Allowances" or RDA) listings for more information.
Your dose needs may change if you have an injury, illness, or infection, if you are pregnant, if you are under stress, or if you exercise more than usual.
Chromium picolinate is only part of a complete program of treatment that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Store chromium picolinate at room temperature away from moisture and heat.
What happens if I miss a dose?
Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking CRM (chromium picolinate)?
Avoid a diet that is high in sugar. It may interfere with the effectiveness of chromium picolinate.
Avoid using antacids without your healthcare provider's advice. Use only the specific type of antacid your healthcare provider recommends. Antacids contain different medicines and some types can make it harder for your body to absorb chromium picolinate.
CRM (chromium picolinate) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects are more likely to occur, and you may have none at all.
Tell your doctor, pharmacist, or healthcare provider about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect CRM (chromium picolinate)?
Do not take chromium picolinate without the advice of a doctor if you are using any of the following medications:
insulin or diabetes medications you take by mouth;
steroid medications (prednisolone and others);
nicotinic acid (niacin, Niaspan, Niacor, Advicor, and others);
stomach acid reducers such as cimetidine (Tagamet), ranitidine (Zantac), famotidine (Pepcid), or nizatidine (Axid);
proton-pump inhibitor acid reducers such as esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), or rabeprazole (Aciphex);
a beta-blocker such as acebutolol (Sectral), atenolol (Tenormin), betaxolol (Kerlone), bisoprolol (Zebeta, Ziac), carteolol (Cartrol), carvedilol (Coreg), esmolol (Brevibloc), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), penbutolol (Levatol), pindolol (Visken), propranolol (Inderal, InnoPran), sotalol (Betapace), or timolol (Blocadren); or
aspirin or an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), indomethacin (Indocin), piroxicam (Feldene), and others.
This list is not complete and other drugs may interact with chromium picolinate. Tell your healthcare provider about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More CRM resources
- CRM Use in Pregnancy & Breastfeeding
- CRM Drug Interactions
- 0 Reviews for CRM - Add your own review/rating
- Chromium Picolinate MedFacts Consumer Leaflet (Wolters Kluwer)
Compare CRM with other medications
- Diabetes, Type 2
- Vitamin/Mineral Supplementation and Deficiency
Where can I get more information?
- Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.
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