Thursday, October 27, 2016

Cortisone


Generic Name: cortisone (KOR ti sone)

Brand Names: Cortone Acetate


What is cortisone?

Cortisone is a steroid that prevents the release of substances in the body that cause inflammation.


Cortisone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.


Cortisone may also be used for purposes not listed in this medication guide.


What is the most important information I should know about cortisone?


You should not use this medication if you are allergic to cortisone, or if you have a fungal infection anywhere in your body.

Before taking cortisone, tell your doctor about all of your medical conditions, and about all other medicines you are using. There are many other diseases that can be affected by steroid use, and many other medicines that can interact with steroids.


Your dosage needs may change if you have surgery, are ill, are under stress, or have a fever or infection. Do not change your medication dose or schedule without your doctor's advice. Tell your doctor about any illness or infection you have had within the past several weeks.


Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using a steroid.


Do not receive a "live" vaccine while using cortisone. The vaccine may not work as well during this time, and may not fully protect you from disease.


Do not stop using cortisone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Wear a medical alert tag or carry an ID card stating that you take cortisone. Any medical care provider who treats you should know that you take steroid medication.

What should I discuss with my healthcare provider before taking cortisone?


You should not use this medication if you are allergic to cortisone, or if you have a fungal infection anywhere in your body.

Steroid medication can weaken your immune system, making it easier for you to get an infection. Steroids can also worsen an infection you already have, or reactivate an infection you recently had. Before taking this medication, tell your doctor about any illness or infection you have had within the past several weeks.


To make sure you can safely take cortisone, tell your doctor if you have any of these other conditions:



  • liver disease (such as cirrhosis);




  • kidney disease;




  • a thyroid disorder;




  • diabetes;




  • a history of malaria;




  • tuberculosis;




  • osteoporosis;




  • a muscle disorder such as myasthenia gravis;




  • glaucoma or cataracts;




  • herpes infection of the eyes;




  • stomach ulcers, ulcerative colitis, or diverticulitis;




  • depression or mental illness;




  • congestive heart failure; or




  • high blood pressure.




It is not known whether cortisone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Cortisone can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using cortisone.

Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.


How should I take cortisone?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


Your doctor may occasionally change your dose to make sure you get the best results.


Your dosage needs may change if you have surgery, are ill, are under stress, or have a fever or infection. Do not change your medication dose or schedule without your doctor's advice. Tell your doctor about any illness or infection you have had within the past several weeks.


This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using cortisone. Do not stop using cortisone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Wear a medical alert tag or carry an ID card stating that you take cortisone. Any medical care provider who treats you should know that you take steroid medication. Store at room temperature away from moisture, heat, and light.

See also: Cortisone dosage (in more detail)

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of cortisone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


What should I avoid while taking cortisone?


Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using a steroid.

Do not receive a "live" vaccine while using cortisone. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), Bacillus Calmette-Guérin (BCG), oral polio, rotavirus, smallpox, typhoid, yellow fever, varicella (chickenpox), H1N1 influenza, and nasal flu vaccine.


Avoid drinking alcohol while you are taking cortisone.

Cortisone side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

  • problems with your vision;




  • swelling, rapid weight gain, feeling short of breath;




  • severe depression, unusual thoughts or behavior, seizure (convulsions);




  • bloody or tarry stools, coughing up blood;




  • pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate);




  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or




  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).



Less serious side effects may include:



  • sleep problems (insomnia), mood changes;




  • acne, dry skin, thinning skin, bruising or discoloration;




  • slow wound healing;




  • increased sweating;




  • headache, dizziness, spinning sensation;




  • nausea, stomach pain, bloating; or




  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Cortisone Dosing Information


Usual Adult Dose for Adrenal Insufficiency:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Idiopathic (Immune) Thrombocytopenic Purpura:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Shock:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Hemolytic Anemia:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Erythroblastopenia:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Loeffler's Syndrome:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Sarcoidosis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Berylliosis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Lymphoma:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Nephrotic Syndrome:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Uveitis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Iritis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Keratitis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Conjunctivitis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Iridocyclitis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Chorioretinitis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Choroiditis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Systemic Lupus Erythematosus:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Dermatomyositis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Ankylosing Spondylitis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Bursitis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Osteoarthritis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Rheumatoid Arthritis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Gouty Arthritis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Psoriatic Arthritis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Epicondylitis:

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Pediatric Dose for Adrenal Insufficiency:

0.5 mg to 0.75 mg/kg/day orally given in equally divided doses every 8 hours. Alternatively, 0.25 mg to 0.35 mg/kg IM once daily


What other drugs will affect cortisone?


Many drugs can interact with cortisone. Below is just a partial list. Tell your doctor if you are using:



  • aspirin (taken on a daily basis or at high doses);




  • a diuretic (water pill);




  • a blood thinner such as warfarin (Coumadin, Jantoven);




  • cyclosporine (Gengraf, Neoral, Sandimmune);




  • insulin or diabetes medications you take by mouth;




  • ketoconazole (Nizoral);




  • rifampin (Rifadin, Rifater, Rifamate, Rimactane); or




  • seizure medications such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton).



This list is not complete and there are many other drugs that can interact with cortisone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.



More cortisone resources


  • Cortisone Side Effects (in more detail)
  • Cortisone Dosage
  • Cortisone Use in Pregnancy & Breastfeeding
  • Drug Images
  • Cortisone Drug Interactions
  • Cortisone Support Group
  • 1 Review for Cortisone - Add your own review/rating


  • Cortisone MedFacts Consumer Leaflet (Wolters Kluwer)

  • Cortisone Acetate Monograph (AHFS DI)



Compare cortisone with other medications


  • Adrenal Insufficiency
  • Ankylosing Spondylitis
  • Berylliosis
  • Bursitis
  • Chorioditis
  • Chorioretinitis
  • Conjunctivitis
  • Dermatomyositis
  • Epicondylitis, Tennis Elbow
  • Erythroblastopenia
  • Gouty Arthritis
  • Hemolytic Anemia
  • Idiopathic Thrombocytopenic Purpura
  • Iridocyclitis
  • Iritis
  • Keratitis
  • Loeffler's Syndrome
  • Lymphoma
  • Nephrotic Syndrome
  • Osteoarthritis
  • Psoriatic Arthritis
  • Rheumatoid Arthritis
  • Sarcoidosis
  • Shock
  • Systemic Lupus Erythematosus
  • Uveitis


Where can I get more information?


  • Your pharmacist can provide more information about cortisone.

See also: cortisone side effects (in more detail)



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