Saturday, November 5, 2016

Chloral Hydrate Suppositories


Generic Name: Chloral Hydrate (KLOR-uhl HYE-drate)
Brand Name: Aquachloral Supprettes


Chloral Hydrate Suppositories are used for:

Treating sleep disorders. It may be used to prevent symptoms of alcohol withdrawal or to treat existing withdrawal symptoms. It may also be used to produce sedation or sleep before certain procedures, or to relieve anxiety due to certain procedures or substance withdrawal. It may also be used along with other medicines after surgery to help decrease pain. It may also be used for other conditions as determined by your doctor.


Chloral Hydrate Suppositories are a nonbarbiturate sedative and hypnotic. It works by depressing the central nervous system (brain). This causes drowsiness and helps you to fall asleep. It is less likely to cause a slower breathing rate than barbiturate-type sedatives/hypnotics.


Do NOT use Chloral Hydrate Suppositories if:


  • you are allergic to any ingredient in Chloral Hydrate Suppositories

  • you have moderate to severe liver or kidney problems, severe heart problems, or severe inflammation of your stomach or rectum

  • you are currently taking dofetilide, H1 antagonists (eg, astemizole, terfenadine), or sodium oxybate (GHB)

  • you have a history of alcohol or other substance abuse or dependence

Contact your doctor or health care provider right away if any of these apply to you.



Before using Chloral Hydrate Suppositories:


Some medical conditions may interact with Chloral Hydrate Suppositories. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have an inflammation of the esophagus, an ulcer, a blood disorder (eg, porphyria), suicidal thoughts, or you have a history of depression

Some MEDICINES MAY INTERACT with Chloral Hydrate Suppositories. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Arsenic, cisapride, dofetilide, or H1 antagonists (eg, astemizole, terfenadine) because side effects, such as serious heart problems, may occur

  • Barbiturates (eg, phenobarbital), paraldehyde, or sodium oxybate (GHB) because the actions and side effects of these medicines may be increased

  • Loop diuretics (eg, furosemide) because unexpected side effects, such as fast heart rate and changing blood pressure, may occur

  • Anticoagulants (eg, warfarin) because actions and side effects may be altered by Chloral Hydrate Suppositoriess

This may not be a complete list of all interactions that may occur. Ask your health care provider if Chloral Hydrate Suppositories may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Chloral Hydrate Suppositories:


Use Chloral Hydrate Suppositories as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • If the suppository is too soft to use, run cold water over it. Then remove the wrapper and moisten the suppository with cool water. Lie down on your side. Insert the pointed end of the suppository into the rectum, then use your finger to push it in completely. Wash your hands thoroughly after using Chloral Hydrate Suppositories.

  • If you miss a dose of Chloral Hydrate Suppositories and you are taking it regularly, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chloral Hydrate Suppositories.



Important safety information:


  • Chloral Hydrate Suppositories may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Chloral Hydrate Suppositories. Using Chloral Hydrate Suppositories alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Chloral Hydrate Suppositories. Chloral Hydrate Suppositories will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Chloral Hydrate Suppositories.

  • Chloral Hydrate Suppositories may contain tartrazine dye (FD&C Yellow No. 5), which can cause allergic reactions in certain patients. If you have previously had an allergic reaction to tartrazine, contact your pharmacist to determine if the medicine you are taking contains tartrazine.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Chloral Hydrate Suppositories during pregnancy. Chloral Hydrate Suppositories are excreted in breast milk. If you are or will be breast-feeding while you are using Chloral Hydrate Suppositories, check with your doctor or pharmacist to discuss the risks to your baby.

Chloral Hydrate Suppositories may be habit-forming and lead to DEPENDENCE if used in high doses or for a long period of time. If you are on long-term or high dosage therapy, you may have WITHDRAWAL symptoms (eg, convulsions, tremor, stomach and muscle cramps, vomiting, sweating) if you suddenly stop taking Chloral Hydrate Suppositories. Do not stop therapy abruptly or change dosage without asking your pharmacist or doctor. Discuss overuse with your doctor or pharmacist.



Possible side effects of Chloral Hydrate Suppositories:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Diarrhea; dizziness; drowsiness upon awakening; gas; nausea; unpleasant taste in mouth; upset stomach.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); disorientation; vomiting.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Chloral Hydrate side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include decreased pupil size; slow or fast and shallow breathing; vomiting.


Proper storage of Chloral Hydrate Suppositories:

Store Chloral Hydrate Suppositories at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Do not refrigerate. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Chloral Hydrate Suppositories out of the reach of children and away from pets.


General information:


  • If you have any questions about Chloral Hydrate Suppositories, please talk with your doctor, pharmacist, or other health care provider.

  • Chloral Hydrate Suppositories are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Chloral Hydrate Suppositories. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Chloral Hydrate resources


  • Chloral Hydrate Side Effects (in more detail)
  • Chloral Hydrate Use in Pregnancy & Breastfeeding
  • Chloral Hydrate Drug Interactions
  • Chloral Hydrate Support Group
  • 10 Reviews for Chloral Hydrate - Add your own review/rating


Compare Chloral Hydrate with other medications


  • Insomnia
  • Sedation


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